Biofilm Formation: Understanding Microbial Communities and Their Clinical Impact
Recognize that biofilms represent one of the most successful survival strategies in microbiology, with sessile bacterial communities exhibiting up to 1,000-fold greater tolerance to antimicrobial agents compared to their planktonic counterparts. This structural organization accounts for approximately 80% of chronic and recurrent human infections, fundamentally altering how we approach treatment protocols in modern healthcare. The extracellular polymeric …
